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two small 12-week, double-blind, randomized trials compared digoxin to placebo in adult patients with chronic congestive heart failure, new york heart association class ii or iii.

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aluminum hydroxide; magnesium hydroxide; simethicone moderate concurrent administration of liquid antacid formulations of aluminum hydroxide can decrease absorption of digoxin and other cardiac glycosides and reduce their plasma concentration.

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in patients with hyperthyroidism, lower digoxin concentrations may result due to an increase in renal clearance of digoxin.

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